- https://www.livescience.com/33179-does-human-body-replace-cells-seven-years.htmlScientists have uncovered evidence showing that some neurons in the hippocampus are renewed, but only at a rate of 1.75% annually, according to a 2013 study in Cell. And some types of neurons within the striatum also regenerate, according to a 2014 study in Cell. But other types of neurons stay with a person for their entire lifetime, Bergmann said. And even the distinct cell populations that can rejuvenate are not replaced entirely, but only partly over a lifetime, he said.
After the early period of growth, suicide, and pruning comes to an end, adult neurons survive for a lifetime.
- https://news.harvard.edu/gazette/story/2022/05/a-tour-of-the-growing-brain-complete-with-upside-down-visionPlus, unlike those of fish, amphibians, and reptiles, human brains don’t regenerate much after injury because only a small number of neurons are born during adulthood.
You'll move on from that, too. You know the stages of mourning? It's like that: eventually, you reach acceptance, make peace with the way of things, and just do what good you can in your small sphere of influence. — Vera Mont
I think so too. It is difficult not to agree with that. Interestingly, as I'm finding to be common, we may arrive at that belief following (at least slightly) divergent paths. — ENOAH
I have never said that. I have never even thought that. What I said is that it would be very difficult for them to live if they lacked the capacity to see, hear, taste, touch and smell from the womb to adulthood.we cannot imagine that her life has value. — ENOAH
I think there are unconscious dynamics involved in thought. — Nemo2124
Thoughts occur in the brain through a complex interaction of neurons and their networks, involving various brain regions, neurotransmitters, and biological processes. The exact mechanisms are still a subject of ongoing research and debate, but here’s a general overview of how thoughts are believed to be generated:
1. Neural Activity
Thought processes are primarily associated with the activity of neurons, the brain's nerve cells. Neurons communicate with each other through electrical impulses and chemical signals (neurotransmitters). Each neuron connects to thousands of other neurons, forming extensive networks that are the basis for all brain functions, including thinking.
2. Brain Regions Involved
Prefrontal Cortex: This front part of the brain is highly involved in complex cognitive behavior, personality expression, decision making, and moderating social behavior. It plays a critical role in planning complex cognitive behavior and in the expression of thoughts.
Temporal Lobes: These areas of the brain are involved in processing sensory input and are important for understanding language, forming memories, and connecting emotions and senses.
Parietal Lobes: These help in processing sensory information and are key to spatial orientation and navigation, which are important for abstract thinking and reasoning.
Occipital Lobes: Primarily associated with visual processing, these areas are also linked with visual aspects of thought, like imagining or recalling images.
Cerebellum and Basal Ganglia: These structures contribute to coordination and smoothing of thought processes, akin to their roles in smoothing and coordinating motor activity.
3. Role of Neurotransmitters
Neurotransmitters are chemicals in the brain that transmit signals from one neuron to another. Different neurotransmitters are associated with different aspects of thought:
Dopamine: Often linked with motivation and reward feelings, influencing focus and attention.
Serotonin: Plays roles in mood regulation, which can affect the overall tone and quality of thoughts.
Acetylcholine: Important for attention and arousal, influencing learning and short-term memory.
Glutamate and GABA: Primary excitatory and inhibitory neurotransmitters in the brain, crucial for balancing activation and relaxation necessary for smooth thought processes.
4. Cognitive Processes
Thinking involves several cognitive processes, including perception, memory, language understanding, and problem-solving. Thoughts can be triggered by external sensory stimuli or internal cues such as emotions or memories. The integration of information from these various sources allows for the formation of thoughts.
5. Formation and Flow of Thoughts
Thoughts can arise from conscious attention or unconscious processes. The brain continuously processes sensory information and internal states even without conscious focus, contributing to spontaneous or background thought generation.
Thoughts are not isolated but are part of a continuous stream of consciousness, influenced by past experiences, knowledge, current goals, and future anticipations.
6. Neuroplasticity
The brain's ability to reorganize itself by forming new neural connections throughout life, known as neuroplasticity, allows for the continuous development and refinement of thought patterns. Learning and experience lead to changes in these connections, affecting how thoughts are generated and processed.
In summary, thoughts are the result of highly complex and dynamic interactions within the brain's neural networks. They are influenced by various factors, including biological, environmental, and experiential elements. The ongoing research in neuroscience continues to unravel the intricacies of how thoughts are formed and manifest in the brain. — ChatGPT 4
Thanks for the welcome. The true nature of the self, to keep it brief, is the being that exists in the mind prior to any sense perception. In other words, there is no self without sense perception of the world.
Monozygotic twins, often called identical twins, originate from the same fertilized egg that splits into two embryos. This shared origin means that they start with the same genetic material. However, saying they are completely genetically identical throughout their lives is an oversimplification due to several factors:
1. Mutations During Development
As the cells of the embryos divide and grow, small mutations can occur. These mutations might be different between the two twins, leading to slight genetic differences as they develop.
2. Epigenetic Differences
While the DNA sequence itself may be very similar, the way this genetic information is expressed can differ due to epigenetic changes. Epigenetics involves modifications that affect gene expression without altering the DNA sequence itself. Factors such as environment, lifestyle, and different experiences can lead to epigenetic changes that differ between the twins, influencing how their genes are expressed.
3. Somatic Mosaicism
Somatic mosaicism refers to the occurrence of two or more genetically different cell lines within the same individual, caused by mutations that occur after fertilization and during cell division. This can also happen independently in each twin, leading to differences between them.
4. Copy Number Variations
Small differences in the number of copies of certain genes can emerge during the early stages of embryonic development after the initial zygotic split. These variations can lead to further genetic divergence between monozygotic twins.
5. Environmental Influences
Even in the womb, monozygotic twins can experience different environments. For example, they might have different positions in the uterus or slightly different nourishment from the placenta. These subtle environmental differences can influence their development, both physically and potentially at the genetic expression level.
While monozygotic twins are genetically very similar compared to other siblings, they are not absolutely identical. The small genetic differences that can arise are typically not significant enough to affect the fact that they are more similar to each other than to anyone else, but these differences can be important in the context of medical research, forensic analysis, and understanding how genes and the environment interact to shape individuals.
