The difference between philosophy and science …question made complicated because “science” or “philosophy” means different things to different people/contexts. With the shifting and inconsistent definitions it could lead to misunderstanding.
I think it was Wittgenstein, somewhere, who said that one of the problems with philosophy is the lack of consensus of what philosophy should entail, conflicting language games.
My initial thoughts, and I stand to be corrected or further elaborated by those with more expertise, is the relevance of methodology.
Hard science (as opposed to soft descriptive science) is more in the business of doing actual experiments, confirming/rejecting measurable hypotheses, ultimately, at least provisionally to establish casual connections, leading to more predictive power etc.
Otoh, philosophy is not usually lab work, but more to question or to clarity these presuppositions, it could for example examine the latent cultural structures in which these operate, or it could be a non-scientific (not anti-science) endeavour putting the emphasis on “being” back to some kind of primordial, non-dualistic thinking.